Pharmacology and Toxicology | Makerere University Courses

Course Code:

BCH 3205

Course Credit Units:

Semester:

Semester 2

Year of Study:

Year 3

Undergraduate or Graduate Level:

Undergraduate Level

College:

College of Natural Sciences

School:

School of Biological Sciences

Department:

Biochemistry

Course Discipline:

Biology

Course Description & Objectives:

This third year course introduces students to the core principles of pharmacology and toxicology. Pharmacokinetics is discussed with emphasis on the ways in which pH affects the pharmacokinetics of a drug. Students are introduced to the major classes of drugs and the modes of action. Toxicology is discussed with emphasis on the biochemical aspects: biotransformation of drugs and the biochemical basis of toxicity.

Learning Outcomes:

At the end of the course students should be able to:

Describe the pharmacokinetics of a drug and the factors that influence it.
State the properties of a receptor
Give the criteria used to define a neurotransmitter
Describe the major neurotransmitters of the peripheral nervous system
Define “agonists” and “antagonists” and give examples from the human nervous system
Describe, with examples, neuropeptides
Describe, with examples, the mode of action of antibiotics
Describe, with examples, the mode of action of non-steroidal anti-inflammatory drugs
Define toxicology
Describe the nature of toxic effects with emphasis on the biochemical basis of toxicity

Outline dose-response relationships

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